Alpha7 Nicotinic Acetylcholine Receptor Mediates Nicotine-induced Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma HepG2 Cells

• Main Authors: Khalil Hajiasgharzadeh (Author), Mohammad Hossein Somi (Author), Behzad Mansoori (Author), Mohammad Amin Doustvandi (Author), Fatemeh Vahidian (Author), Mohsen Alizadeh (Author), Ahad Mokhtarzadeh (Author), Dariush Shanehbandi (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The cytotoxic properties upon treatment with nicotine have been reported in several studies, but the underlying mechanisms remain not fully defined. The alpha7 nicotinic acetylcholine receptor (α7nAChR) is one of the important nicotinic receptors, which nicotine partly by binding to this re...