Formation and Characterisation of Posaconazole Hydrate Form

• Hoofdauteurs: Michail Lykouras (Auteur), Malvina Orkoula (Auteur), Christos Kontoyannis (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Posaconazole is an API added as Form I for the production of oral suspensions, but it is found as Form-S in the final formulation. In this study, it was found that this polymorphic conversion, which may affect the bioavailability, is due to an interaction with water. However, the relatively poor wet...