Tumour Cell Lines HT-29 and FaDu Produce Proinflammatory Cytokines and Activate Neutrophils In Vitro: Possible Applications for Neutrophil-Based Antitumour Treatment

• Main Authors: Antonio Brú (Author), Juan-Carlos Souto (Author), Sonia Alcolea (Author), Rosa Antón (Author), Angel Remacha (Author), Mercedes Camacho (Author), Marta Soler (Author), Isabel Brú (Author), Amelia Porres (Author), Luis Vila (Author)
• Format: Book
• Published: Hindawi Limited, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is evidence that polymorphonuclear neutrophils (PMNs) can exert severe antineoplastic effects. Cross-talk between tumour cells and endothelial cells (ECs) is necessary for the accumulation of PMN around a tumour. This work reports the ability of two PMN-sensitive, human, permanent cell lines-c...