Cholesterol Stimulates the Transient Receptor Potential Melastatin 4 Channel in mpkCCDc14 Cells

• Main Authors: Yong-Xu Cai (Author), Bao-Long Zhang (Author), Miao Yu (Author), Yan-Chao Yang (Author), Xue Ao (Author), Di Zhu (Author), Qiu-Shi Wang (Author), Jie Lou (Author), Chen Liang (Author), Liang-Liang Tang (Author), Ming-Ming Wu (Author), Zhi-Ren Zhang (Author), He-Ping Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have shown that cholesterol regulates the activity of ion channels in mouse cortical collecting duct (CCD) mpkCCDc14 cells and that the transient receptor potential melastatin 4 (TRPM4) channel is expressed in these cells. However, whether TRPM4 channel is regulated by cholesterol remains unclear...