Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

<p>Abstract</p> <p>Background</p> <p>The key co-repressor complex components HDAC-2, Mi-2α/β and mSin3a are all critical to the regulation of gene transcription. HDAC-2 function is impaired by oxidative stress in a PI3Kδ dependant manner which may be involved in the chr...

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Main Authors: Chung Kian (Author), Stevenson Christopher S (Author), Marwick John A (Author), Adcock Ian M (Author), Kirkham Paul A (Author)
Format: Book
Published: BMC, 2010-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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