HSA-based multi-target combination therapy: regulating drugs' release from HSA and overcoming single drug resistance in a breast cancer model

• Main Authors: Yi Gou (Author), Zhenlei Zhang (Author), Dongyang Li (Author), Lei Zhao (Author), Meiling Cai (Author), Zhewen Sun (Author), Yongping Li (Author), Yao Zhang (Author), Hamid Khan (Author), Hongbing Sun (Author), Tao Wang (Author), Hong Liang (Author), Feng Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multi-drug delivery systems, which may be promising solution to overcome obstacles, have limited the clinical success of multi-drug combination therapies to treat cancer. To this end, we used three different anticancer agents, Cu(BpT)Br, NAMI-A, and doxorubicin (DOX), to build human serum albumin (H...