Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells

• मुख्य लेखकों: Keisuke Migita (लेखक), Taichi Matsumoto (लेखक), Kazuki Terada (लेखक), Kazuhiko Ono (लेखक), Shuji Hara (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2019-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Heat shock protein 90 (HSP90) antagonists are currently being evaluated as potential anticancer drugs. However, adverse effects related to these drugs, such as fatigue and pain, suggest that they affect neurons. Therefore, to understand the influence of HSP90 inhibitors on neurons, we investigated t...