In vitro characterization and cellular uptake profiles of TAMs-targeted lipid calcium carbonate nanoparticles for cancer immunotherapy

• Main Authors: Xiaoyan Xu (Author), Renjie Li (Author), Runqi Dong (Author), Yanfang Yang (Author), Hongliang Wang (Author), Jialing Cheng (Author), Yuling Liu (Author), Jun Ye (Author)
• Format: Book
• Published: Compuscript Ltd, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated macrophages (TAMs) are key contributors to tumor development, accelerated tumor invasion and metastasis, and induction of immunosuppression. Targeted delivery of immunomodulatory agents to promote polarization of TAMs may alleviate the immunosuppressive tumor microenvironment. Calci...