Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways

Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways

The binding of p-coumaroyl glucose to glycogen phosphorylase (GP; a pharmaceutical target for the development of antihyperglycaemic drugs) has been studied by kinetics, and X-ray crystallography while its effect to HepG2 cells metabolism has been assessed by NMR metabolomics. p-Coumaroyl glucose is...

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Main Authors: Anastasia S. Tsagkarakou (Author), Styliani A. Chasapi (Author), Symeon M. Koulas (Author), Ioannis Tsialtas (Author), Efthimios Kyriakis (Author), Christina E. Drakou (Author), Sándor Kun (Author), László Somsák (Author), Georgios A. Spyroulias (Author), Anna-Maria G. Psarra (Author), Demetres D. Leonidas (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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