CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters

• Main Authors: Fani Karagianni (Author), Ching-Ni Njauw (Author), Katerina P. Kypreou (Author), Aravela Stergiopoulou (Author), Michaela Plaka (Author), Dorothea Polydorou (Author), Vasiliki Chasapi (Author), Leontios Pappas (Author), Ioannis A. Stratigos (Author), Gregory Champsas (Author), Peter Panagiotou (Author), Helen Gogas (Author), Evangelos Evangelou (Author), Hensin Tsao (Author), Alexander J. Stratigos (Author), Irene Stefanaki (Author)
• Format: Book
• Published: Medical Journals Sweden, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Approximately 5-10% of melanoma cases occur in a familial context. CDKN2A/CDK4 were the first high-penetrance melanoma genes identified. The aims of this study were to evaluate CDKN2A/CDK4 variants in Greek familial melanoma patients and to correlate the mutational status with specific clinico-epide...