HtrA1 expression and the prognosis of high-grade serous ovarian carcinoma: a cohort study using digital analysis

• Main Authors: Andréanne Gagné (Author), Bernard Têtu (Author), Michèle Orain (Author), Stéphane Turcotte (Author), Marie Plante (Author), Jean Grégoire (Author), Marie-Claude Renaud (Author), Isabelle Bairati (Author), Dominique Trudel (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The expression of high temperature requirement factor A1 (Htra1) has been reported to be decreased in ovarian carcinoma, but its prognostic effect remains undetermined. Methods We evaluated the impact of HtrA1 downregulation in tumoral tissues on cancer progression and death in w...