Hydroquinone 5-<i>O</i>-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc

• Autori principali: Nattamon Hongwiangchan (Autore), Nicharat Sriratanasak (Autore), Duangdao Wichadakul (Autore), Nithikoon Aksorn (Autore), Supakarn Chamni (Autore), Pithi Chanvorachote (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Cancer stem cells (CSCs) are distinct cancer populations with tumorigenic and self-renewal abilities. CSCs are drivers of cancer initiation, progression, therapeutic failure, and disease recurrence. Thereby, novel compounds targeting CSCs offer a promising way to control cancer. In this study, the h...