Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts

• Main Authors: Armando Alcazar Magana (Author), Ralph L. Reed (Author), Rony Koluda (Author), Cristobal L. Miranda (Author), Claudia S. Maier (Author), Jan F. Stevens (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vitamin C (L-ascorbic acid, AA) is an essential cellular antioxidant and cofactor for several α-ketoglutarate-dependent dioxygenases. As an antioxidant, AA interacts with vitamin E to control oxidative stress. While several reports suggest an interaction of AA with folate (vitamin B9) in an...