Enhancement of Trk Signaling Pathways by the Cholestane Amide Conjugate MCC-257

• Main Authors: Maki K. Yamada (Author), Yoshiyuki Konishi (Author), Bunpei Kakinoki (Author), Koji Ikegami (Author), Mitsutoshi Setou (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2008-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The cholestane amide conjugate MCC-257 has been shown to augment the effects of nerve growth factor (NGF) on cell survival and on tyrosine phosphorylation of the TrkA receptor in PC12 cells. Recent findings suggest that signaling pathways downstream of Trk are regulated independently. We describe he...