Musashi-2 contributes to myotonic dystrophy muscle dysfunction by promoting excessive autophagy through miR-7 biogenesis repression
Skeletal muscle symptoms strongly contribute to mortality of myotonic dystrophy type 1 (DM1) patients. DM1 is a neuromuscular genetic disease caused by CTG repeat expansions that, upon transcription, sequester the Muscleblind-like family of proteins and dysregulate alternative splicing of hundreds o...
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Main Authors: | , , , , , |
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Formato: | Libro |
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Elsevier,
2021-09-01T00:00:00Z.
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Número de Clasificación: |
A1234.567 |
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