Loss of KDM4B impairs osteogenic differentiation of OMSCs and promotes oral bone aging

• Main Authors: Peng Deng (Author), Insoon Chang (Author), Jiongke Wang (Author), Amr A. Badreldin (Author), Xiyao Li (Author), Bo Yu (Author), Cun-Yu Wang (Author)
• Format: Book
• Published: Nature Publishing Group, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aging of craniofacial skeleton significantly impairs the repair and regeneration of trauma-induced bony defects, and complicates dental treatment outcomes. Age-related alveolar bone loss could be attributed to decreased progenitor pool through senescence, imbalance in bone metabolism and bo...