Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery

• Main Authors: Erica Quagliarini (Author), Serena Renzi (Author), Luca Digiacomo (Author), Francesca Giulimondi (Author), Barbara Sartori (Author), Heinz Amenitsch (Author), Valentina Tassinari (Author), Laura Masuelli (Author), Roberto Bei (Author), Lishan Cui (Author), Junbiao Wang (Author), Augusto Amici (Author), Cristina Marchini (Author), Daniela Pozzi (Author), Giulio Caracciolo (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years, lipid nanoparticles (LNPs) have gained considerable attention in numerous research fields ranging from gene therapy to cancer immunotherapy and DNA vaccination. While some RNA-encapsulating LNP formulations passed clinical trials, DNA-loaded LNPs have been only marginally explored s...