Targeting the Mitotic Catastrophe Signaling Pathway in Cancer
Mitotic catastrophe, as defined in 2012 by the International Nomenclature Committee on Cell Death, is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and responds by driving a cell to an irreversible antiproliferative fate of death or senescence. Thus, failed mitotic cata...
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2015-01-01T00:00:00Z.
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