Population Pharmacokinetic Analysis Proves Superiority of Continuous Infusion in PK/PD Target Attainment with Oxacillin in Staphylococcal Infections

Population Pharmacokinetic Analysis Proves Superiority of Continuous Infusion in PK/PD Target Attainment with Oxacillin in Staphylococcal Infections

Considering its very short elimination half-life, the approved oxacillin dosage might not be sufficient to maintain the pharmacokinetic/pharmacodynamics (PK/PD) target of time-dependent antibiotics. This study aimed to describe the population pharmacokinetics of oxacillin and to explore the probabil...

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Main Authors: Irena Murínová (Author), Martin Švidrnoch (Author), Tomáš Gucký (Author), Jan Hlaváč (Author), Pavel Michálek (Author), Ondřej Slanař (Author), Martin Šíma (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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