METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis

• Autori principali: Qiuchan Xiong (Autore), Caojie Liu (Autore), Xin Zheng (Autore), Xinyi Zhou (Autore), Kexin Lei (Autore), Xiaohan Zhang (Autore), Qian Wang (Autore), Weimin Lin (Autore), Ruizhan Tong (Autore), Ruoshi Xu (Autore), Quan Yuan (Autore)
• Natura: Libro
• Pubblicazione: Nature Publishing Group, 2022-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract The dorsal lingual epithelium, which is composed of taste buds and keratinocytes differentiated from K14+ basal cells, discriminates taste compounds and maintains the epithelial barrier. N6-methyladenosine (m6A) is the most abundant mRNA modification in eukaryotic cells. How METTL3-mediated...