Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds

CYP2A6 is a human enzyme responsible for the metabolic elimination of nicotine, and it is also involved in the activation of procarcinogenic nitrosamines, especially those present in tobacco smoke. Several investigations have reported that reducing this enzyme activity may contribute to anti-smoking...

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Main Authors: Daniela Andrea Ramirez (Author), Eduardo Marchevsky (Author), Juan Maria Luco (Author), Alejandra Camargo (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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