EZH2 Protein Expression and Tumor Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

• Main Authors: Lucienne Pereira Del Grossi Neusquen (Author), José Roberto Filassi (Author), Carlos Elias Fristachi (Author), Kátia Candido Carvalho (Author), Maíra Teixeira Dória (Author), José Maria Soares Júnior (Author), José Roberto Morales Piato (Author)
• Format: Book
• Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Neoadjuvant chemotherapy (NAC) is the standard treatment for locally advanced breast cancer. However, some tumors will not respond to this treatment due to histological and molecular features. The protein EZH2 (enhancer of zest homolog 2) is a histone methyltransferase that is...