Umbelliprenin Suppresses Angiogenesis Signaling in SKBR-3 Cell Line by Downregulation of EGF/CoCl2 -Mediated PI3K/AKT/MAPK

• Main Authors: Roya Atabakhshian (Author), Siamak Salami (Author), Reza Mirfakhraie (Author), Somayeh Mahmoodi Khatonabadi (Author), Majid Sirati-Sabet (Author), Bahram Gholamali Yaghmaei (Author), Shiva Ghafghazi (Author), Amirreza Dowlati Beirami (Author), Mitra Sadat Rezaei (Author), Seyed Ali Ziai* (Author)
• Format: Book
• Published: Iranian Society of Pharmacognosy, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objectives: Umbelliprenin, a prenylated coumarin from different species of Ferula, has demonstrated anti-cancer effects in various types of cancer cells, but the potential molecular mechanisms for the anti-angiogenic activity of umbelliprenin in breast cancer cells have not yet been s...