Application of machine learning to predict unbound drug bioavailability in the brain

Purpose: Optimizing brain bioavailability is highly relevant for the development of drugs targeting the central nervous system. Several pharmacokinetic parameters have been used for measuring drug bioavailability in the brain. The most biorelevant among them is possibly the unbound brain-to-plasma p...

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Main Authors: J. Francisco Morales (Author), M. Esperanza Ruiz (Author), Robert E. Stratford (Author), Alan Talevi (Author)
Format: Book
Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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