DNA methylation microarrays identify epigenetically regulated lipid related genes in obese patients with hypercholesterolemia

• Main Authors: Teresa Płatek (Author), Anna Polus (Author), Joanna Góralska (Author), Urszula Raźny (Author), Anna Gruca (Author), Beata Kieć-Wilk (Author), Piotr Zabielski (Author), Maria Kapusta (Author), Krystyna Słowińska-Solnica (Author), Bogdan Solnica (Author), Małgorzata Malczewska-Malec (Author), Aldona Dembińska-Kieć (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Epigenetics can contribute to lipid disorders in obesity. The DNA methylation pattern can be the cause or consequence of high blood lipids. The aim of the study was to investigate the DNA methylation profile in peripheral leukocytes associated with elevated LDL-cholesterol level...