In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanoparticles for siRNA Delivery

• Main Authors: Isabel Ferreiro (Author), Coralie Genevois (Author), Karidia Konate (Author), Eric Vivès (Author), Prisca Boisguérin (Author), Sébastien Deshayes (Author), Franck Couillaud (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small interfering RNA (siRNA) exhibits a high degree of specificity for targeting selected genes. They are efficient on cells in vitro, but in vivo siRNA therapy remains a challenge for solid tumor treatment as siRNAs display difficulty reaching their intracellular target. The present study was desi...