In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanoparticles for siRNA Delivery

• Үндсэн зохиолчид: Isabel Ferreiro (Зохиогч), Coralie Genevois (Зохиогч), Karidia Konate (Зохиогч), Eric Vivès (Зохиогч), Prisca Boisguérin (Зохиогч), Sébastien Deshayes (Зохиогч), Franck Couillaud (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Small interfering RNA (siRNA) exhibits a high degree of specificity for targeting selected genes. They are efficient on cells in vitro, but in vivo siRNA therapy remains a challenge for solid tumor treatment as siRNAs display difficulty reaching their intracellular target. The present study was desi...