Weekly Oral Tenofovir Alafenamide Protects Macaques from Vaginal and Rectal Simian HIV Infection

• Main Authors: Ivana Massud (Author), Kenji Nishiura (Author), Susan Ruone (Author), Angela Holder (Author), Chuong Dinh (Author), Jonathan Lipscomb (Author), James Mitchell (Author), George M. Khalil (Author), Walid Heneine (Author), J. Gerardo Garcίa-Lerma (Author), Charles W. Dobard (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pre-exposure prophylaxis (PrEP) with a weekly oral regimen of antiretroviral drugs could be a suitable preventative option for individuals who struggle with daily PrEP or prefer not to use long-acting injectables. We assessed in macaques the efficacy of weekly oral tenofovir alafenamide (TAF) at dos...