Cereblon-Recruiting PROTACs: Will New Drugs Have to Face Old Challenges?

The classical low-molecular-weight drugs are designed to bind with high affinity to the biological targets endowed with receptor or enzymatic activity, and inhibit their function. However, there are many non-receptor or non-enzymatic disease proteins that seem undruggable using the traditional drug...

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Autores principales: Marcin Cieślak (Autor), Marta Słowianek (Autor)
Formato: Libro
Publicado: MDPI AG, 2023-03-01T00:00:00Z.
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