Cereblon-Recruiting PROTACs: Will New Drugs Have to Face Old Challenges?
The classical low-molecular-weight drugs are designed to bind with high affinity to the biological targets endowed with receptor or enzymatic activity, and inhibit their function. However, there are many non-receptor or non-enzymatic disease proteins that seem undruggable using the traditional drug...
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MDPI AG,
2023-03-01T00:00:00Z.
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