Development of a Monomeric Inhibitory RNA Aptamer Specific for FGFR3 that Acts as an Activator When Dimerized

There have been limited options for people who suffer from fibroblast growth factor receptor (FGFR) signaling disorders. In this study, we developed RNA aptamers specific for FGFR3 as potential therapeutic agents. Using a structured aptamer library, we performed ten rounds of SELEX (systematic evolu...

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Bibliographic Details
Main Authors: Nachiket Kamatkar (Author), Matthew Levy (Author), Jean M. Hébert (Author)
Format: Book
Published: Elsevier, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available