Simultaneous measurement of tadehaginoside and its principal metabolite in rats by HPLC-MS/MS and its application in pharmacokinetics and tissue distribution study

• Main Authors: Cai-Yun Zhang (Author), Ya-Ting Lu (Author), Yin-Feng Tan (Author), Qi-Bing Liu (Author), Lin Dong (Author), Ning Ma (Author), Wei-Ying Lu (Author), Zhi-Heng Su (Author), Xiao-Po Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Tadehaginoside, an active ingredient isolated from Tadehagi triquetrum (Linn.) Ohashi (Leguminosae), exhibited various biological activities. However, the pharmacokinetics and tissue distribution which affect tadehaginoside's therapeutic actions and application remain elusive. Objective...