Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release

• Main Authors: Michael P. Greenwood (Author), Mingkwan Greenwood (Author), Soledad Bárez-López (Author), Joe W. Hawkins (Author), Katherine Short (Author), Danijela Tatovic (Author), David Murphy (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: The excessive release of the antidiuretic hormone vasopressin is implicated in many diseases including cardiovascular disease, diabetes, obesity, and metabolic syndrome. Once thought to be elevated as a consequence of diseases, data now supports a more causative role. We have previously...