Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo

• 主要な著者: Zhuo Han (著者), Xingming Zhao (著者), E Zhang (著者), Jiahui Ma (著者), Hao Zhang (著者), Jianjiang Li (著者), Weidong Xie (著者), Xia Li (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Resistomycin, a quinone-related natural antibiotic, has shown strong inhibitory activity against human hepatocellular carcinoma (HCC) in vitro. Here, we investigated the role of p38 MAPK in the pro-apoptotic and G2/M phase arrest action of HCC HepG2 cells upon treatment with resistomycin in vitro an...