Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo

Resistomycin, a quinone-related natural antibiotic, has shown strong inhibitory activity against human hepatocellular carcinoma (HCC) in vitro. Here, we investigated the role of p38 MAPK in the pro-apoptotic and G2/M phase arrest action of HCC HepG2 cells upon treatment with resistomycin in vitro an...

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Main Authors: Zhuo Han (Author), Xingming Zhao (Author), E Zhang (Author), Jiahui Ma (Author), Hao Zhang (Author), Jianjiang Li (Author), Weidong Xie (Author), Xia Li (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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