Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides

• Main Authors: Jennifer Pfeil (Author), Mario Simonetti (Author), Uta Lauer (Author), Bianca von Thülen (Author), Pawel Durek (Author), Christina Poulsen (Author), Justyna Pawlowska (Author), Matthias Kröger (Author), Ralf Krähmer (Author), Frank Leenders (Author), Ute Hoffmann (Author), Alf Hamann (Author)
• Format: Book
• Published: SAGE Publishing, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Therapeutic treatment options for chronic autoimmune disorders such as multiple sclerosis (MS) rely largely on the use of non-specific immunosuppressive drugs, which are not able to cure the disease. Presently, approaches to induce antigen-specific tolerance as a therapeutic approach; fo...