Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia

• Autores principales: Ai-ris Yonekura Collier (Autor), Zsuzsanna Zsengeller (Autor), Elizabeth Pernicone (Autor), Saira Salahuddin (Autor), Eliyahu V. Khankin (Autor), S. Ananth Karumanchi (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2019-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The immune complement system protects against pathogens; however, excess activation results in disease like hemolytic uremic syndrome, a clinical imitator of preeclampsia. Vascular endothelial factor (VEGF) protects against aberrant complement activation and is inhibited by soluble fms-like tyrosine...