Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport

• Main Authors: Antonella Obinu (Author), Giovanni Pietro Burrai (Author), Roberta Cavalli (Author), Grazia Galleri (Author), Rossana Migheli (Author), Elisabetta Antuofermo (Author), Giovanna Rassu (Author), Elisabetta Gavini (Author), Paolo Giunchedi (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genistein (GEN) is a soy-derived isoflavone that exhibits several biological effects, such as neuroprotective activity and the prevention of several types of cancer and cardiovascular disease. However, due to its poor water solubility and the extensive first-pass metabolism, the oral bioavailability...