Pretomanid dose selection for pulmonary tuberculosis: An application of multi‐objective optimization to dosage regimen design
Abstract Clinical development of combination chemotherapies for tuberculosis (TB) is complicated by partial or restricted phase II dose‐finding. Barriers include a propensity for drug resistance with monotherapy, practical limits on numbers of treatment arms for component dose combinations, and limi...
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| Format: | Book |
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Wiley,
2021-03-01T00:00:00Z.
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