Testis- specific Y-encoded- like protein 1 and cholesterol metabolism: Regulation of CYP1B1 expression through Wnt signaling

• Main Authors: Xiujuan Zhu (Author), Huanyao Gao (Author), Sisi Qin (Author), Duan Liu (Author), Junmei Cairns (Author), Yayun Gu (Author), Jia Yu (Author), Richard M. Weinshilboum (Author), Liewei Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cytochromes P450 (CYPs) represent a large gene superfamily that plays an important role in the metabolism of both exogenous and endogenous compounds. We have reported that the testis-specific Y-encoded-like proteins (TSPYLs) are novel CYP gene transcriptional regulators. However, little is known...