Pretreatment with LCK inhibitors chemosensitizes cisplatin‐resistant endometrioid ovarian tumors

• Main Authors: Katie K. Crean-Tate (Author), Chad Braley (Author), Goutam Dey (Author), Emily Esakov (Author), Caner Saygin (Author), Alexandria Trestan (Author), Daniel J. Silver (Author), Soumya M. Turaga (Author), Elizabeth V. Connor (Author), Robert DeBernardo (Author), Chad M. Michener (Author), Peter G. Rose (Author), Justin Lathia (Author), Ofer Reizes (Author)
• 格式: 图书
• 出版: BMC, 2021-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Ovarian cancer is the most fatal gynecologic malignancy in the United States. While chemotherapy is effective in the vast majority of ovarian cancer patients, recurrence and resistance to standard systemic therapy is nearly inevitable. We discovered that activation of the non-rec...