Recent findings in the regulation of G6PD and its role in diseases

• Main Authors: Qingfei Meng (Author), Yanghe Zhang (Author), Shiming Hao (Author), Huihui Sun (Author), Bin Liu (Author), Honglan Zhou (Author), Yishu Wang (Author), Zhi-Xiang Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP to synthesize ribonucleotides and maintain intracellular redox homeostasis. G6PD expression can be abnormally elevated in a varie...