Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer

• Main Authors: A. W. Adamson (Author), Y. C. Ding (Author), L. Steele (Author), L. A. Leong (Author), R. Morgan (Author), M. T. Wakabayashi (Author), E. S. Han (Author), T. H. Dellinger (Author), P. S. Lin (Author), A. A. Hakim (Author), S. Wilczynski (Author), C. D. Warden (Author), S. Tao (Author), V. Bedell (Author), M. C. Cristea (Author), S. L. Neuhausen (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background High-grade serous ovarian cancers (HGSCs) display a high degree of complex genetic alterations. In this study, we identified germline and somatic genetic alterations in HGSC and their association with relapse-free and overall survival. Using a targeted capture of 557 genes involv...