Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis

• Main Authors: Gemmati Donato (Author), Zeri Giulia (Author), Orioli Elisa (Author), De Gaetano Francesca E (Author), Salvi Fabrizio (Author), Bartolomei Ilaria (Author), D'Alfonso Sandra (Author), Dall'Osso Claudia (Author), Leone Maurizio A (Author), Singh Ajay V (Author), Asselta Rosanna (Author), Zamboni Paolo (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Iron involvement/imbalance is strongly suspected in multiple sclerosis (MS) etiopathogenesis, but its role is quite debated. Iron deposits encircle the veins in brain MS lesions, increasing local metal concentrations in brain parench...