iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study

• Main Authors: Peter D. Westenskow (Author), Felicitas Bucher (Author), Stephen Bravo (Author), Toshihide Kurihara (Author), Daniel Feitelberg (Author), Liliana P. Paris (Author), Edith Aguilar (Author), Jonathan H. Lin (Author), Martin Friedlander (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phototransduction is accomplished in the retina by photoreceptor neurons and retinal pigment epithelium (RPE) cells. Photoreceptors rely heavily on the RPE, and death or dysfunction of RPE is characteristic of age-related macular degeneration (AMD), a very common neurodegenerative disease for which...