TLR7 activation in M-CSF-dependent monocyte-derived human macrophages potentiates inflammatory responses and prompts neutrophil recruitment

Toll-like receptor 7 (TLR7) is an endosomal Pathogen-Associated Molecular Pattern (PAMP) receptor that senses single-stranded RNA (ssRNA) and whose engagement results in the production of type I IFN and pro-inflammatory cytokines upon viral exposure. Recent genetic studies have established that a dy...

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主要な著者: Miriam Simón-Fuentes (著者), Cristina Herrero (著者), Lucia Acero-Riaguas (著者), Concha Nieto (著者), Fatima Lasala (著者), Nuria Labiod (著者), Joanna Luczkowiak (著者), Bárbara Alonso (著者), Rafael Delgado (著者), Maria Colmenares (著者), Ángel L. Corbí (著者), Ángeles Domínguez-Soto (著者)
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出版事項: Karger Publishers, 2023-04-01T00:00:00Z.
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3rd Floor Main Library

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