Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects

• Principais autores: Kevin Clare (Autor), Chelsea Pan (Autor), Gloria Kim (Autor), Kicheon Park (Autor), Juan Zhao (Autor), Nora D. Volkow (Autor), Zhicheng Lin (Autor), Congwu Du (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Addiction to cocaine is associated with dysfunction of the dopamine mesocortical system including impaired dopamine-2 receptor (D2r) signaling. However, the effects of chronic cocaine on neuronal adaptations in this system have not been systematically examined and data available is mostly from males...