Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis

• Main Authors: Louisane Desbiens (Author), Catherine Lapointe (Author), Marjan Gharagozloo (Author), Shaimaa Mahmoud (Author), Gunnar Pejler (Author), Denis Gris (Author), Pedro D'Orléans-Juste (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Experimental autoimmune encephalomyelitis (EAE) is a mouse model that reproduces cardinal signs of clinical, histopathological, and immunological features found in Multiple Sclerosis (MS). Mast cells are suggested to be involved in the main inflammatory phases occurring during EAE development, possi...