The effect of long-acting PDE-5 inhibitor on renal ischemia/ reperfusion injury in Wistar rats; a study on serum cystatin C and renal histopathological findings

• প্রধান লেখক: Safendra Siregar (লেখক), Tjahjodjati Romdam (লেখক), Henry Stanzah (লেখক), Irfan Firmansyah (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Society of Diabetic Nephropathy Prevention, 2019-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Ischemia/reperfusion (I/R) is often a complication of bleeding shock, renal dysfunction and renal vessel operation. Nitric oxide (NO) as an important vasodilator is produced by endothelial cells. NO stimulates the generation of cyclic guanosine monophosphate (cGMP). Phosphodiesterase (PD...