Activated mast cells in skeletal muscle can be a potential mediator for cancer‐associated cachexia

• Autors principals: D. Brooke Widner (Autor), Chun Liu (Autor), Qingxia Zhao (Autor), Sarah Sharp (Autor), Matthew R. Eber (Autor), Sun H. Park (Autor), D. Clark Files (Autor), Yusuke Shiozawa (Autor)
• Format: Llibre
• Publicat: Wiley, 2021-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Eighty per cent of United States advanced cancer patients faces a worsened prognosis due to cancer‐associated cachexia. Inflammation is one driver of muscle atrophy in cachexia, and skeletal muscle‐resident immune cells could be a source of inflammation. This study explores the e...