Activated mast cells in skeletal muscle can be a potential mediator for cancer‐associated cachexia

• Main Authors: D. Brooke Widner (Author), Chun Liu (Author), Qingxia Zhao (Author), Sarah Sharp (Author), Matthew R. Eber (Author), Sun H. Park (Author), D. Clark Files (Author), Yusuke Shiozawa (Author)
• Format: Book
• Published: Wiley, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Eighty per cent of United States advanced cancer patients faces a worsened prognosis due to cancer‐associated cachexia. Inflammation is one driver of muscle atrophy in cachexia, and skeletal muscle‐resident immune cells could be a source of inflammation. This study explores the e...