Enzymatic shaving of the tegument surface of live schistosomes for proteomic analysis: a rational approach to select vaccine candidates.

• Main Authors: William Castro-Borges (Author), Adam Dowle (Author), Rachel S Curwen (Author), Jane Thomas-Oates (Author), R Alan Wilson (Author)
• 格式: 图书
• 出版: Public Library of Science (PLoS), 2011-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The membrane-associated and membrane-spanning constituents of the Schistosoma mansoni tegument surface, the parasite's principal interface with the host bloodstream, have recently been characterized using proteomic techniques. Biotinylation of live worms using membrane-impermeant probes reveale...