Pharmacological and toxicological studies of a novel goserelin acetate extended-release microspheres in rats

• Main Authors: Mao Yutong (Author), Ye Liang (Author), Sha Chunjie (Author), Guan Xiaolin (Author), Gong Xiaoyan (Author), Dong Lin (Author), Du Guangying (Author), Zhang Xuemei (Author), Cen Xiaobo (Author), Tian Jingwei (Author), Yu Pengfei (Author), Wang Hongbo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

LY01005 is an investigational new drug product of goserelin acetate which is formulated as extended-release microspheres for intramuscular injection. To support the proposed clinical trials and marketing application of LY01005, pharmacodynamics, pharmacokinetics and toxicity studies were performed i...